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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis

Fig. 2

Supernatants from HSC increased the percentages of Th17 cells and Tregs. a Phenotypes of primary HSC extracted from HBV-related fibrotic liver tissues in Group 2. Sections were immunostained with desmin, FAP, FSP, vimentin, fibronectin and a-SMA antibodies. One of 20 representative micrographs is shown. b, d Purified CD4+ T cells were cultured alone (Blank) or with 30% indicated supernatants. The values in the quadrants represent the percentages of Th17 cells and Tregs. The data shown are representative dot plots from more than three independent experiments. c, e The statistical analysis of the effect of LX-2 and pHSC supernatant on the percentages of Th17 cells (c) and Tregs (e). *p < 0.05, **p < 0.01, ***p < 0.001

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