From: Urinary collagen degradation products as early markers of progressive renal fibrosis
 | uC3M/Cr 6 weeks | uC1M/Cr 6 weeks | ||
---|---|---|---|---|
Rs | P value | Rs | P value | |
A. | ||||
 ADR untreated rats | ||||
  Histological markers—12 weeks | ||||
   Collagen type III | 0.381 | 0.352 | 0.262 | 0.531 |
   Fibronectin | 0.238 | 0.570 | 0.190 | 0.651 |
   Myofibroblasts(α-SMA) | 0.333 | 0.420 | 0.310 | 0.456 |
   PDGF-β receptor | 0.524 | 0.183 | 0.405 | 0.320 |
   Tubulointerstitial fibrosis (PAS) | 0.687 | 0.060 | 0.674 | 0.067 |
   Hyaluronan | 0.810 | 0.015 | 0.571 | 0.139 |
 | uC3M/Cr 12 weeks | uC1M/Cr 12 weeks | ||
---|---|---|---|---|
Rs | P value | Rs | P value | |
B. | ||||
 ADR-rats (pooled) | ||||
  Histological markers—12 weeks | ||||
   Collagen type III | 0.529 | 0.035 | 0.403 | 0.122 |
   Fibronectin | 0.074 | 0.787 | 0.194 | 0.471 |
   Myofibroblasts(α-SMA) | 0.600 | 0.014 | 0.497 | 0.050 |
   PDGF-β receptor | 0.841 | <0.0001 | 0.656 | 0.006 |
   Tubulointerstitial fibrosis (PAS) | 0.831 | 0.000 | 0.694 | 0.003 |
   Hyaluronan | 0.807 | 0.000 | 0.654 | 0.006 |