|
Assay or measurement
|
Study cohort
|
Mean ± SEM
|
p value
|
|---|
|
Age (years)
|
Control
|
36.83 ± 2.03
|
0.78
|
|
CFS/ME
|
37.69 ± 1.78
|
|
Haemoglobin (g/L)
|
Control
|
140.89 ± 2.48
|
0.64
|
|
CFS/ME
|
139.13 ± 2.12
|
|
Thyroid stimulating hormone (mIU/L)
|
Control
|
1.38 ± 0.16
|
0.72
|
|
CFS/ME
|
1.45 ± 0.10
|
|
Vitamin D (nmol/L)
|
Control
|
73.61 ± 7.73
|
0.71
|
|
CFS/ME
|
76.64 ± 3.99
|
|
Anion gap (mmol/L)
|
Control
|
11.49 ± 0.55
|
0.14
|
|
CFS/ME
|
10.62 ± 0.30
|
|
GTT–blood glucose 30 min post load (mmol/L)
|
Control
|
7.15 ± 0.52
|
0.45
|
|
CFS/ME
|
7.66 ± 0.27
|
|
GTT–blood insulin 30 min post load (mU/L)
|
Control
|
50.88 ± 9.80
|
0.07
|
|
CFS/ME
|
81.33 ± 6.76
|
|
Interleukin-2 (pg/mL)
|
Control
|
0.22 ± 0.12
|
0.09
|
|
CFS/ME
|
0.54 ± 0.11
|
|
Interleukin-4 (pg/mL)
|
Control
|
0.26 ± 0.14
|
0.15
|
|
CFS/ME
|
0.55 ± 0.11
|
|
Interleukin-6 (pg/mL)
|
Control
|
0.86 ± 0.25
|
0.20
|
|
CFS/ME
|
1.37 ± 0.20
|
|
Interleukin-10 (pg/mL)
|
Control
|
1.06 ± 0.16
|
0.43
|
|
CFS/ME
|
1.18 ± 0.09
|
|
Interleukin-17A (pg/mL)
|
Control
|
Not detected
|
N/A
|
|
CFS/ME
|
Not detected
|
|
Interferon-γ (pg/mL)
|
Control
|
0.57 ± 0.20
|
0.31
|
|
CFS/ME
|
0.37 ± 0.11
|
|
Tumour necrosis factor (pg/mL)
|
Control
|
Not detected
|
N/A
|
|
CFS/ME
|
Not detected
|
- Analyses comprised healthy controls (n = 17) and the CFS/ME cohort (n = 45), except for cytokine and GTT studies that compared n = 8–10 controls with n = 38–44 CFS/ME. Statistical significance was calculated by unpaired Mann–Whitney test
-
GTT glucose tolerance test
