Fig. 6
Effect of luteolin on tumor growth in vivo and effect of Notch1 on prognosis. a Images of MKN-28 xenograft tumors treated with PBS or luteolin. b Tumor volumes were measured every week (*P < 0.05, **P < 0.01). c Average weights of xenograft tumors in nude mice (*P < 0.05). d Expression of β-catenin, Notch1, and Ki-67 in xenograft tumors by IHC (200×). e TUNEL staining of xenograft tumors (200×). f, g Higher expression of Notch1 was correlated to a poor overall survival (OS) (P = 0.00022) and poor time to first progression (FP) (P = 0.00062)