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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway

Fig. 3

Effects of luteolin on cytoskeleton and motility in GC cells. NCI-N87 GC cells were treated with or without luteolin (30 μM) for 24 h, and analyzed by F-actin staining (Red F-actin, Blue DAPI, 200×). a Control NCI-N87 GC cells showed a spindle and fusiform shape, which indicates higher motility. b Luteolin treatment (30 μM) for 24 h caused shrinking in NCI-N87 GC cells and a decrease in the number of pseudopodia on the cell surface. c, d The cell motility was assessed by transwell assays (200×). e, f The number of migrating and invading cells is quantified. Results are the means of three independent experiments. *P < 0.05, **P < 0.01

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