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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

Fig. 2

Representative IHC staining patterns with COX-2-specific mAb (clone CX-294) of FFPE primary (a, b, c) and metastatic lymph node (d, e, f) from a total of 44 primary and 45 not matched metastatic melanoma tumors. COX-2 expression was reviewed and enumerated independently and blindly by two experienced pathologists (GB and AA). COX-2 expression was scored as variations in the percentage of stained cells at 10% intervals. Staining was graded as a semi-quantitative variable. Results ranged from 0 to 80% of positive melanoma cells. Percentage of COX-2 positive cells, tumor margin (dotted line) and magnification are indicated. Arrows indicate examples of COX-2 positive melanoma cells

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