Fig. 1
From: COX-2 expression positively correlates with PD-L1 expression in human melanoma cells
Representative IHC staining patterns with PD-L1-specific mAb (clone SP-142) of FFPE primary (a, b, c) and metastatic lymph node (d, e, f) from a total of 44 primary and 45 not matched metastatic melanoma tumors. PD-L1 expression was reviewed and enumerated independently and blindly by two experienced pathologists (GB and AA). PD-L1 expression was scored as negative (0+) (a, d), light positive (1+) (b, e) and positive (2+) (c, f) when the PD-L1 score in an entire lesion was 0, 1–5, and >5% respectively. Magnification is indicated. Arrows indicate examples of PD-L1 positive melanoma cells