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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab

Fig. 2

Heatmap of 15 analytes selected Week 6: Expression pattern of 15 cytokines that respond differently to stimulation with NY-ESO-1 versus gp-100 and MART-1 at week 6 (p value <0.05): IL-1β, VEGF, G-CSF, HGF, IL-13, IL-17, GM-CSF, MCP-1, IL-5, IL-7, IL-4, IL-10, IFN-γ, IL-8 and IL-2 Patients were clustered into 2 groups: six patients in cluster 1: 1, 5, 6, 7, 8, and 9 tend to have better RFS and they also have higher cytokine expression when stimulated with NY-ESO-1

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