Fig. 1

Heatmap of 17 analytes selected at Baseline: Expression pattern of 17 cytokines that respond differently to stimulation with NY-ESO-1 vs. gp-100 and MART-1 at baseline (p value <0.05): IL1β, MIP1β, IL1RA, VEGF, IL13, IL17, MIP1α, GM-CSF, MCP1, IL5, IL2R, IL4, IL10, IFN-γ, TNFα, IL8 and IL2. Patients were clustered into 2 groups: seven patients in cluster 1: 1, 5, 6, 7, 8, 9, and 10 tend to have better RFS and they also have higher cytokine expression when stimulated with NY-ESO-1