Fig. 5

External features characteristics of HFD-dNONcNZO fetuses at the time of Caesarean section at GD 18.5. Although normal craniofacial and midline phenotypes were seen in less than 10% of the cases such as those in a and e respectively, microphthalmia (micro) in b, protruding tongue (pt), anophthalmia (an) and exencephaly (ex) in c, swollen forebrain (sfb) and open eye (oe) in d, and omphalocele (omph) in f were the most frequent defects in the offspring of diabetic HFD-dNONcNZO dams