Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis

Table 1 Diagnostic sensitivity of some biomarkers in inflammatory myopathies

Diseases	Markers			Sensitivity (%)	Specificity (%)
Controls
All	β-actin	PKM2	βF1/Hsp60	96	100
DM	PKM2			100	100
sIBM	β-actin	βF1/LDHA		100	100
DM
All	βF1/PKM2			95	100
CTR				100	100
PM				100	100
sIBM				90	100

The table summarizes the power to discriminate (sensitivity) the myopathies by the value of the indicated markers. Sensitivity was calculated accordingly to the classification rate of the positive samples following the formula: Sensitivity = true positives/(true positives + false positives). Specificity = true negatives/(true negatives + false positives)

ISSN: 1479-5876