Table 3 Multivariate Cox regression analysis
Disease-free survival | HR | 95% CI | p value |
|---|---|---|---|
Number of positive nodes | |||
 ≥4 versus 1–3 | 2.51 | 1.88–3.63 | <0.001 |
Tumor size | |||
 2–5 cm versus ≤2 cm | 1.45 | 1.08–1.95 | 0.013 |
 >5 cm versus ≤2 cm | 1.65 | 1.10–2.48 | 0.015 |
Adjuvant HT | |||
 Yes versus no | 0.69 | 0.51–0.93 | 0.016 |
OPN mRNA expression | |||
 High versus low | 1.34 | 1.04–1.71 | 0.022 |
Overall survival | |||
Number of positive nodes | |||
 ≥4 versus 1–3 | 3.59 | 2.48–5.19 | <0.001 |
Tumor size | |||
 2–5 cm versus ≤2 cm | 1.59 | 1.13–2.34 | 0.009 |
 >5 cm versus ≤2 cm | 1.87 | 1.18–2.97 | 0.008 |
Adjuvant HT | |||
 Yes versus no | 0.55 | 0.39–0.76 | <0.001 |
OPN mRNA expression | |||
 High versus low | 1.54 | 1.16–2.05 | 0.003 |