Table 1 Overview of GBM patient characteristics, molecular alterations, cryoperiod of the samples prior to subcutaneous implantation and outcome of PDX establishment attempts in NMRI Foxn1^nu mice

HROG02

M/68

P53 (R248Q), 3xEGFR, MGMT(M)

305

–

HROG04

F/53

36xEGFR, MGMT(U)

270

–

588

–

826

–

HROG05

F/60

82xEGFR, K-ras (G12D), MGMT(M)

268

✓

HROG06

M/53

P53 (R273H, R306*), 82xEGFR, MGMT(U)

260

–

570

✓

HROG07

M/55

12xEGFR, MGMT(U)

143

–

699

–

HROG10

M/74

MGMT(U)

71

–

627

–

HROG11

F/54

P53 (R248Q), 3xEGFR, MGMT(U)

56

–

HROG12

M/64

36xEGFR, MGMT(U)

307

✓

HROG13

F/77

MGMT(U)

318

–

529

✓

HROG15

M/56

n.d.

240

–

HROG16

M/53

MGMT(U)

237

–

HROG17

M/70

3xEGFR, MGMT(M)

194

✓

HROG19

M/69

8xEGFR, MGMT(U)

217

–

HROG21

M/44

IDH1 (R132H), MGMT(U)

192

–

HROG22

M/66

MGMT(M)

167

–

HROG23

F/60

BRAF (V600E), MGMT(U)

191

–

1057

–

HROG24

F/73

P53 (R273C), 42xEGFR, MGMT(U)

112

–

350

–

HROG25

F/77

MGMT(U)

117

–

HROG31

F/59

MGMT(U)

55

–

214

–

HROG32

F/76

44xEGFR, MGMT(U)

125

–

HROG33

F/46

31xEGFR, MGMT(U)

119

✓

HROG34

F/69

96xEGFR, MGMT(U)

133

–

HROG36

F/80

MGMT(U)

80

–

HROG38

F/49

MGMT(U)

58

–

236

–

HROG41

M/71

IDH1 (R132H), MGMT(M)

31

–

209

–

HROG42

F/70

MGMT(U)

30

–

189

–

HROG49

M/45

MGMT(U)

Fresh

–

360

–

HROG52

M/47

n.d.

Fresh

✓

308

–

HROG54

M/58

MGMT(M)

Fresh

–

281

–

HROG55

F/74

MGMT(M)

Fresh

–

278

–

HROG56

F/76

MGMT(U)

Fresh

–

222

–

HROG58

F/57

MGMT(U)

Fresh

–

165

–

HROG59

M/60

16xEGFR, MGMT(U)

Fresh

✓

152

–

HROG60

M/51

2xEGFR, MGMT(U)

Fresh

–

126

–

513

–

HROG63

M/48

18xEGFR, MGMT(U)

Fresh

–

20

–

HROG64

F/57

MGMT(M)

Fresh

–

20

–