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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Towards standardization of next-generation sequencing of FFPE samples for clinical oncology: intrinsic obstacles and possible solutions

Fig. 2

The mutations counts correlate with the pre-normalization library concentrations. Samples with highest pre-normalization library concentrations were found to harbor fewer mutations, most probably due to lower amounts of DNA degradation artifacts, while samples with lowest pre-normalization library concentrations harbored a diverse spectrum of the detectable variants (Spearman’s rank correlation −0.81; p < 1e−10)

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