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Table 5 Changes in neurodevelopment test scores according to randomization

From: Neuroregenerative potential of intravenous G-CSF and autologous peripheral blood stem cells in children with cerebral palsy: a randomized, double-blind, cross-over study

  Before randomization (M0–M1) After randomization (M1–M7 or M7–M13) p*
Placebo mPBMC p +
GMFM 1.6738 0.4000 0.3725 0.479 0.001
PEDI_C 2.2787 0.5180 0.4928 0.764 0.006
PEDI_M 3.0212 0.6187 0.5419 0.998 0.005
PEDI_F 3.6106 0.6665 0.6536 0.930 0.042
PEDI_CC 2.4127 0.6115 0.5549 0.736 0.057
PEDI_MC 1.3191 0.5366 0.2558 0.092 0.030
PEDI_FC 2.5148 1.1481 0.6079 0.040 0.022
QUEST 9.0497 1.0815 1.3392 0.949 0.047
  1. mPBMC mobilized peripheral blood marrow cell; GMFM gross motor function measure; PEDI_C pediatric evaluation of disability inventory self-care; PEDI_M pediatric evaluation of disability inventory mobility; PEDI_F pediatric evaluation of disability inventory social function; PEDI_CC pediatric evaluation of disability inventory mobility self-care with caregiver assistance; PEDI_MC pediatric evaluation of disability inventory mobility with caregiver assistance; PEDI_FC pediatric evaluation of disability inventory mobility social function with caregiver assistance; QUEST quality of upper extremity skills test
  2. M0, M1, M7 and M13 refer to months after enrollment
  3. + p indicates statistical significances of items between placebo and mPBMC groups
  4. * p indicates statistical significances of items between before randomization and after randomization
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