Fig. 1

Design of the clinical study. MRI-DTI magnetic resonance imaging-diffusion tensor imaging; PET positron emission tomography; G-CSF granulocyte colony-stimulating factor; mPBMC mobilized peripheral blood mononuclear cell. M0, M1, M7 and M13 refer to months after enrollment. T1 and T7 refer to a group who received mPBMC at 1 and 7 months of study, respectively