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Table 1 Candidate demographics, cPRA and clinical outcomes

From: B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy

 

Controls (n = 7)

Responders (n = 11)

Non-responders (n = 8)

Age (years)

45 ± 11

40 ± 12

43 ± 7

Male/female

4/3

7/4

2/6

Race

 White

3

3

4

 Black

1

3

1

 Hispanic

1

1

3

 Asian

2

3

0

 Native American

0

1

0

Cause of ESRD

   

 Diabetes

0

2

1

 Glomerulonephritis

4

1

1

 SLE

1

3

1

 PKD

0

1

1

 Congenital

0

3

0

 Other

2

1

4

Cumulative cPRA (%)

 Before desensitization

13 ± 16

97.4 ± 2.7

100 ± 0

 After desensitization

N/A

87.9 ± 3.8

100 ± 0

Transplanted (%)

7 (100)

11 (100)

3 (37.5)

Donor type: DD:LUR:LRD

1:0:6

8:2:1

2:1:0

Rejection

 Borderline acute

0

3 (27)

1 (33)

 Cell mediated

0

1 (9)

0

 Antibody mediated

0

0

0

Graft loss (%)

0

0

0

Death-censored graft survival (1 year)

100%

100%

100%

  1. SLE systemic lupus erythematosus, PKD polycystic kidney disease, DD deceased donor, LUR living unrelated, LRD living related donor