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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Two differentially structured collagen scaffolds for potential urinary bladder augmentation: proof of concept study in a Göttingen minipig model

Fig. 1

Study design. a Isolation and cultivation of primary cells from Göttingen minipig urinary bladder. Seeding of scaffolds was performed after 3 weeks and implantation of seeded scaffolds into the pig bladder after another 3 weeks. b During OPI two OptiMaix 2D (oval) and 3D (square) each, without cells, were implanted into the ventral bladder wall. c During OPII, one of the implanted OptiMaix 2D and 3D each, was excised and substituted by a fresh unseeded scaffold of the same make and shape. Two autologously seeded OptiMaix 2D scaffolds were implanted into the right and one autologously seeded OptiMaix 3D scaffold was implanted in the left dorsal bladder wall. After OPI 15.4% and after OPII 24.7% of the native tissue had been substituted by the OptiMaix scaffolds

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