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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Increased T cell breadth and antibody response elicited in prime-boost regimen by viral vector encoded homologous SIV Gag/Env in outbred CD1 mice

Fig. 3

Heterologous Gag immunization does not induce more cross reactive T cell responses. At day 69 mice were sacrificed and spleens were harvested for analysis of vaccine induced T cell responses against HIV-1 CON B Gag, SIVmac239 Gag, and SIVagm vervet Gag. a Number of IFN-γ positive CD8+ T cells measured at day 69 against full length Gag. b Number of IFN-γ positive CD8+ T cells measured at day 69 against CE of the three Gag variants. Shown are calculated total numbers of responding CD8+ T cells per spleen of individual mice. Horizontal lines depict the mean of the groups

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