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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2

Fig. 5

P21 and p27 expression were repressed by MALAT1 associating with EZH2. a, b ChIP analysis of Mino (a) and Jeko-1 (b) cells transfected with si-NC and si-MALAT1 were conducted on CDKN1A/p21 and CDKN1B/p27 promoter regions using anti-EZH2 antibody. c, d ChIP-qPCR analysis of H3k27me3 levels at the promoters of CDKN1A/p21 and CDKN1B/p27 using si-NC and si-MALAT1 transfected cells, Mino (c) and Jeko-1 (d). Data are mean ± S.D. from experiments with three replicates. **P < 0.01, ***P < 0.001

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