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Table 2 Differences of methylation levels (%) between patients with and without CarAC

From: CDKN2B methylation is associated with carotid artery calcification in ischemic stroke patients

Gene Position CarAC p value
With Without
CDKN2A 1 4.4 (3.0–6.0) 4.1 (2.7–5.9) 0.480
2 7.1 (5.3–8.9) 6.7 (5.4–8.5) 0.520
3 8.2 (6.8–10.7) 8.0 (6.3–9.6) 0.130
4 5.8 (4.2–8.0) 5.8 (4.3–7.7) 0.896
5 4.8 (4.0–5.5) 5.1 (4.1–5.5) 0.181
6 2.7 (2.3–3.4) 2.7 (2.3–3.2) 0.592
7 2.3 (1.9–2.8) 2.2 (1.7–2.8) 0.062
8 4.3 (3.8–5.0) 4.4 (3.6–5.2) 0.598
9 4.4 (2.4–8.2) 4.4 (2.5–7.7) 0.845
10 2.1 (1.0–3.2) 1.8 (0.9–3.0) 0.377
11 3.7 (2.5–4.9) 3.5 (2.3–5.0) 0.679
12 0.9 (0.5–1.3) 0.9 (0.6–1.4) 0.745
13 1.2 (0.9–1.5) 1.3 (1.0–1.5) 0.325
14 1.2 (1.0–1.5) 1.2 (0.9–1.4) 0.468
15 2.1 (1.7–2.3) 2.0 (1.6–2.5) 0.482
16 1.3 (1.0–1.7) 1.3 (1.0–1.7) 0.800
17 3.3 (2.7–4.2) 3.1 (2.6–3.5) 0.001
18 2.2 (1.7–2.6) 2.2 (1.8–2.6) 0.937
19 2.5 (2.0–3.0) 2.5 (2.0–2.9) 0.806
20 2.7 (2.1–3.3) 2.7 (2.3–3.2) 0.615
21 15.6 (13.6–17.8) 15.3 (13.9–16.8) 0.511
22 2.5 (2.0–3.1) 2.6 (2.1–3.2) 0.425
23 4.3 (3.5–5.1) 4.3 (3.5–5.0) 0.983
24 1.7 (1.2–2.5) 1.8 (1.3–2.5) 0.449
Average 4.0 (3.6–4.3) 3.9 (3.6–4.2) 0.277
CDKN2B 1 5.5 (4.5–6.4) 5.2 (4.2–6.1) 0.046
2 4.4 (3.4–5.3) 4.3 (3.3–5.2) 0.395
3 3.8 (3.1–4.9) 4.0 (3.1–4.6) 0.890
4 4.2 (3.4–5.1) 4.1 (3.3–4.8) 0.233
5 7.6 (6.6–8.9) 7.2 (6.3–8.1) 0.002
6 6.9 (5.7–8.2) 6.5 (5.3–7.4) 0.009
7 8.3 (7.1–9.6) 7.5 (6.7–8.2) <0.001
8 3.5 (2.9–4.2) 3.3 (2.9–3.7) 0.039
9 4.0 (3.3–4.5) 3.6 (3.0–4.1) <0.001
10 6.1 (5.2–7.1) 5.6 (4.6–6.3) <0.001
11 7.5 (6.3–8.7) 6.8 (6.0–7.8) 0.007
12 5.7 (4.9–6.7) 5.4 (4.6–6.0) 0.009
Average 5.7 (5.0–6.4) 5.4 (4.7–5.9) 0.001
  1. Statistically signficant values are in italics
  2. For each CpG site, p < 0.05/36 after Bonferroni correction, and p < 0.025 for average levels