Table 2 Differences of methylation levels (%) between patients with and without CarAC

4.4 (3.0–6.0)

4.1 (2.7–5.9)

0.480

7.1 (5.3–8.9)

6.7 (5.4–8.5)

0.520

8.2 (6.8–10.7)

8.0 (6.3–9.6)

0.130

5.8 (4.2–8.0)

5.8 (4.3–7.7)

0.896

4.8 (4.0–5.5)

5.1 (4.1–5.5)

0.181

2.7 (2.3–3.4)

2.7 (2.3–3.2)

0.592

2.3 (1.9–2.8)

2.2 (1.7–2.8)

0.062

4.3 (3.8–5.0)

4.4 (3.6–5.2)

0.598

4.4 (2.4–8.2)

4.4 (2.5–7.7)

0.845

2.1 (1.0–3.2)

1.8 (0.9–3.0)

0.377

3.7 (2.5–4.9)

3.5 (2.3–5.0)

0.679

0.9 (0.5–1.3)

0.9 (0.6–1.4)

0.745

1.2 (0.9–1.5)

1.3 (1.0–1.5)

0.325

1.2 (1.0–1.5)

1.2 (0.9–1.4)

0.468

2.1 (1.7–2.3)

2.0 (1.6–2.5)

0.482

1.3 (1.0–1.7)

1.3 (1.0–1.7)

0.800

3.3 (2.7–4.2)

3.1 (2.6–3.5)

0.001

2.2 (1.7–2.6)

2.2 (1.8–2.6)

0.937

2.5 (2.0–3.0)

2.5 (2.0–2.9)

0.806

2.7 (2.1–3.3)

2.7 (2.3–3.2)

0.615

15.6 (13.6–17.8)

15.3 (13.9–16.8)

0.511

2.5 (2.0–3.1)

2.6 (2.1–3.2)

0.425

4.3 (3.5–5.1)

4.3 (3.5–5.0)

0.983

1.7 (1.2–2.5)

1.8 (1.3–2.5)

0.449

4.0 (3.6–4.3)

3.9 (3.6–4.2)

0.277

5.5 (4.5–6.4)

5.2 (4.2–6.1)

0.046

4.4 (3.4–5.3)

4.3 (3.3–5.2)

0.395

3.8 (3.1–4.9)

4.0 (3.1–4.6)

0.890

4.2 (3.4–5.1)

4.1 (3.3–4.8)

0.233

7.6 (6.6–8.9)

7.2 (6.3–8.1)

0.002

6.9 (5.7–8.2)

6.5 (5.3–7.4)

0.009

8.3 (7.1–9.6)

7.5 (6.7–8.2)

<0.001

3.5 (2.9–4.2)

3.3 (2.9–3.7)

0.039

4.0 (3.3–4.5)

3.6 (3.0–4.1)

<0.001

6.1 (5.2–7.1)

5.6 (4.6–6.3)

<0.001

7.5 (6.3–8.7)

6.8 (6.0–7.8)

0.007

5.7 (4.9–6.7)

5.4 (4.6–6.0)

0.009

5.7 (5.0–6.4)

5.4 (4.7–5.9)

0.001