Fig. 5
From: Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes
The levels of proinflammatory cytokines in the follow-up. Serum concentrations of IL6 (upper panel) TNFα (middle panel) and IL1 (bottom panel) were measured during the follow-up. The values for untreated controls (NO Tregs), patients treated with a single infusion (single dose) and patients treated with two infusions (two doses) of Tregs are presented as medians (min.–max.), open circles represent values from particular patients. The p values and short lines represent the significance of Wilcoxon test comparisons immediately after Tregs infusions in treated groups; p values and long lines represent the significance of Wilcoxon’ test comparisons between day 0 vs. the 12 month in the untreated group and day-10 vs. the 24th month in treated groups