Fig. 6From: Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunctionEMPs increased TNF-α and IL-6 release in mouse and decreased NO generation in the mouse hearts. A, B The levels of TNF-α and IL-6 in mouse plasma in EMPs group (5 × 105/mL) were significantly higher than that in control groups. (*P < 0.05 compared with control group, n = 8). C EMPs significantly decrease NO production in the mouse hearts. The group of EMPs (5 × 105/mL) was released NO less than the group of EMPs (105/mL). (*P < 0.05 compared with control group, # P < 0.05 compared with group of EMPs (105/mL), n = 12)Back to article page