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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The magnitude of nephron number reduction mediates intrauterine growth-restriction-induced long term chronic renal disease in the rat. A comparative study in two experimental models

Fig. 3

Renal structure in IUGR-BET offspring more affected than in IUGR-LPD offspring. Nephron number (A), glomerular sclerosis (B), and mean glomerular volume (MGV; C) in 22-month-old normal birth weight (NBW, open bars), maternal low-protein diet (LPD, grey bars), and BET (BET, black bars) offspring, according to gender (n = 8–12/group). Glomerular sclerosis is expressed as the mean ratio of Sirius red-stained areas to total glomerular capillary areas. Value are mean ± SEM; (n = 8–10). Significance differences (p < 0.05) among groups are indicated by different letters (e.g., a is different from b and c)

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