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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: The magnitude of nephron number reduction mediates intrauterine growth-restriction-induced long term chronic renal disease in the rat. A comparative study in two experimental models

Fig. 2

Renal functions in IUGR-BET offspring more affected than in IUGR-LPD offspring. Glomerular filtration rate [evaluated by clearance of creatinine (ClCr)] (A) and proteinuria (B) in normal birth weight (NBW, open bars), maternal low-protein diet (LPD, grey bars), and BET (black bars) offspring at 8, 12, and 15 months after birth, according to gender. Values are mean ± SEM (n = 10–12/group). Significance differences (p < 0.05) among groups are indicated by different letters (e.g., a is different from b). Group effect < 0.01, postnatal age effect <0.001, and combined effects <0.001

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