Fig. 2

Differentially expressed lncRNAs in HBV-, HCV-, and HDV-related HCC, non-HCC cirrhosis and normal livers. a Study design illustrating the different groups of patients. b Hierarchical clustering based on the 10 lncRNAs differentially expressed in HBV-, HCV-, and/or HDV-related HCC. LncRNAs that are up-regulated are shown in shades of red; those down-regulated are shown in shades of blue. The intensity of the color in each cell reflects the level of the corresponding lncRNA in the corresponding patient expressed as normalized log₂ ratios. HCC-T, denotes hepatocellular carcinoma; HCC-NT, denotes surrounding non-tumorous tissue; CIR, denotes cirrhosis without HCC; NL, denotes normal liver from liver donors or liver resection for angioma. c Summary of dysregulatd lncRNAs in different hepatitis viruses-associated HCC tissues compared to their surrounding non-tumorous tissues. Names of up-regulated lncRNAs in HCC are shown in red and those down-regulated are shown in blue