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Table 2 CD4 T cell counting in absolute count and percentage in 150 HIV-1-infected patients living in Central African Republic, including 124 adults, 10 adolescents, 13 children and 3 infants, by the single-platform Muse™ Auto CD4/CD4% system and by the BD FACSCount system

From: Performance evaluation of the touchscreen-based Muse™ Auto CD4/CD4% single-platform system for CD4 T cell numeration in absolute number and in percentage using blood samples from children and adult patients living in the Central African Republic

Categories Adults, adolescents and children ≥ 5 years Children < 5 years and infants
Number 140 10
Absolute CD4 T cells (cells/µl)
 Muse™ Auto CD4/CD4% system
  Mean ± SD 1003 ± 1397 1263 ± 1081
 BD FACSCount system
  Mean ± SD 940 ± 1325 1203 ± 1056
 Absolute bias (limits of agreement)a
  Mean (±1.96 SD) +62.5 (−77.4; +202.4) +60.0 (10.1; +109.8)
Percent CD4 T cells (%CD4)
 Muse™ Auto CD4/CD4% system
  Mean ± SD 15.5 ± 20.5 17.5 ± 14.8
 BD FACSCount system
  Mean ± SD 13.0 ± 18.4 18.0 ± 16.9
 Absolute bias (limits of agreement)a
  Mean (±1.96 SD) +2.5 (−1.6; +6.7) −0.5 (−4.6; +3.6)
  1. SD standard deviation
  2. aThe Bland–Altman analysis was carried out to calculate the absolute bias and limits of agreement which are the 95% confidence intervals (±1.96 × SD) of the mean bias of all paired measurements in a given category (27)