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Table 2 CD4 T cell counting in absolute count and percentage in 150 HIV-1-infected patients living in Central African Republic, including 124 adults, 10 adolescents, 13 children and 3 infants, by the single-platform Muse™ Auto CD4/CD4% system and by the BD FACSCount system

From: Performance evaluation of the touchscreen-based Muse™ Auto CD4/CD4% single-platform system for CD4 T cell numeration in absolute number and in percentage using blood samples from children and adult patients living in the Central African Republic

Categories

Adults, adolescents and children ≥ 5 years

Children < 5 years and infants

Number

140

10

Absolute CD4 T cells (cells/µl)

 Muse™ Auto CD4/CD4% system

  Mean ± SD

1003 ± 1397

1263 ± 1081

 BD FACSCount system

  Mean ± SD

940 ± 1325

1203 ± 1056

 Absolute bias (limits of agreement)a

  Mean (±1.96 SD)

+62.5 (−77.4; +202.4)

+60.0 (10.1; +109.8)

Percent CD4 T cells (%CD4)

 Muse™ Auto CD4/CD4% system

  Mean ± SD

15.5 ± 20.5

17.5 ± 14.8

 BD FACSCount system

  Mean ± SD

13.0 ± 18.4

18.0 ± 16.9

 Absolute bias (limits of agreement)a

  Mean (±1.96 SD)

+2.5 (−1.6; +6.7)

−0.5 (−4.6; +3.6)

  1. SD standard deviation
  2. aThe Bland–Altman analysis was carried out to calculate the absolute bias and limits of agreement which are the 95% confidence intervals (±1.96 × SD) of the mean bias of all paired measurements in a given category (27)