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Table 1 Baseline characteristics of the participants according to incident CKD status

From: Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation

Characteristics Non-CKD Incident CKD P value
n, % 1905 (90.6) 198 (9.4)
Age (years) 58.9 ± 8.9 63.1 ± 10.1 <0.0001
Male (n, %) 753 (39.5) 73 (36.9) 0.47
BMI (kg/m2) 24.7 ± 3.4 25.5 ± 3.8 0.0006
Waist circumference (cm) 86.3 ± 9.4 89.5 ± 9.7 <0.0001
Current drinker (n, %) 344 (18.1) 40 (20.2) 0.58
Current smoker (n, %) 382 (20.1) 39 (19.7) 0.81
SBP (mmHg) 134 ± 24 144 ± 27 <0.0001
DBP (mmHg) 78 ± 10 81 ± 10 0.001
Triglyceride (mmol/l) 1.40 (0.96–2.02) 1.48 (1.01–2.41) 0.02
LDL-C (mmol/l) 2.40 ± 0.68 2.35 ± 0.68 0.30
HDL-C (mmol/l) 1.37 ± 0.30 1.34 ± 0.31 0.31
Total cholesterol (mmol/l) 5.15 ± 0.96 5.11 ± 1.05 0.64
FPG (mmol/l) 5.1 (4.7–5.8) 5.6 (5.0–7.0) <0.0001
HbA1c (%) 6.1 (5.7–6.5) 6.4 (5.9–7.6) <0.0001
TSH (μIU/ml) 1.44 (1.03–2.14) 1.44 (1.01–2.07) 0.35
FT3 (pmol/l) 4.65 ± 0.55 4.72 ± 1.11 0.16
FT4 (pmol/l) 14.27 ± 1.80 14.85 ± 2.36 <0.0001
TPOAb (IU/ml) 0.30 (0.17–0.73) 0.32 (0.18–0.71) 0.55
TGAb (IU/ml) 1.06 (0.71–2.44) 0.93 (0.71–1.91) 0.09
eGFR (ml/min/1.73 m2) 92.4 ± 12.2 88.9 ± 14.4 0.0001
Urinary ACR (mg/g) 4.67 (2.39–8.71) 9.57 (4.41–16.87) <0.0001
Use of antidiabetic drugs (n, %) 208 (10.9) 52 (26.3) <0.0001
Use of antihypertensive drugs (n, %) 426 (22.4) 63 (31.8) 0.003
  1. P values are calculated by t test for continuous variables and Chi-square test for categorical variables
  2. Data are means ± standard deviations or medians (interquartile ranges) for continuous variables, and numbers (proportions) for categorical variables
  3. ACR albumin-to-creatinine ratio, BMI body mass index, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, FT3 free triiodothyronine, FT4 free thyroxine, FPG fasting plasma glucose, HDL-c high-density lipoprotein cholesterol, HbA1c hemoglobin A1c, LDL-c low-density lipoprotein cholesterol, SBP systolic blood pressure, TSH thyroid-stimulating hormone, TPOAb thyroid peroxidase antibody, TGAb thyroglobulin antibody