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Table 1 Identification of quadruple wild-type GIST (qWT) Subset in 186 GIST

From: FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors

Category Number of patientsa Percent of patients (%)
KIT mutated 129 69
PDGFRA mutated 22 12
NF1 mutated 18 10
SDH [ABCD] mutated 14 8
BRAF mutated 7 4
[KNH] RAS mutated 4
qWT 12
SDH unknown 12
  1. aGenomic alterations are not mutually exclusive and are potentially germline (e.g., NF1 and SDH [ABCD]). Of the 162 non-WT GISTs, 32 tumors had one or more genomic alterations in KIT, PDGFRA, NF1, SDH [A-D], BRAF, and/or [KNH] RAS