From: Changes in ceftriaxone pharmacokinetics/pharmacodynamics during the early phase of sepsis: a prospective, experimental study in the rat
 Hours
SHAMÂ +Â CTX (mg/L)
CLPÂ +Â CTX (mg/L)
2
5.7 ± 0.6
5.0 ± 0.7
4
2.7 ± 1.2
2.6 ± 0.7
6
0.4 ± 1.7
1.0 ± 0.2