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Table 4 Storage lesion of the IND (ancillary studies on the IND, to determine maximum shelf life)

From: Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans

Parameter 24 h 48 h 72 h p values (24 vs 28 h) p values (24 vs 72 h)
Cell number [absolute values] 1.7E7 (1.9E7/7.7E6) 1.6E7 (1.7E7/1.1E7) 1.1E7 (1.6E7/1.0E7) p = 0.74, not significant p = 0.31, not significant
Cell number [% 24 h] 100 (100/100) 95 (100/77.9) 74.1 (87/64.7) p = 0.17, not significant p = 0.005, significant
Vital cells [% BMC] 98.8 (98.8/98.4) 96.9 (96.9/96.9) 92.21 (94.0/84.1) p = 0.11, not significant p = 0.043, significant
Vital cells [% 24 h] 100 (100/100) 98.0 (98.9/97.1) 94.4 (97.3/85.2) p = 0.06, trend p = 0.003, significant
CD34+ CD45+ [% BMC] 1.33 (1.95/1.13) 1.47 (1.85/1.24) 1.32 (1.36/1.15) p = 1.0, not significant p = 0.81, not significant
CD34+ CD45+ CD133+ [% BMC] 0.66 (0.75/0.04) 0.6 (0.95/0.43) 0.55 (0.65/0.5) p = 1.0, not significant p = 1.0, not significant
CD45− CD271+ [% BMC] 0.01 (0.03/0.01) 0.03 (0.03/0.03) 0.02 (0.03/0.01) 1.0, not significant 1.0, not significant
CFU-F [1.0E6 BMC] 21.0 (1.95/1.13) 3.0 (9.5/2.5) 1.0 (3.0/0.5) p = 0.1, trend p = 0.04, significant
CFU-F [% of 24 h] 100.0 (100/100) 22.0 (9.7/76.2) 3.2 (0/23.8) p = 0.04, significant p = 0.03, significant