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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Pulsed high-dose dexamethasone modulates Th1-/Th2-chemokine imbalance in immune thrombocytopenia

Fig. 3

Relative quantification of mRNA levels of CCR5, CXCR3, and CCR3. a Compared to control, CCR5 mRNA levels in active ITP patients were elevated (P = 0.000 < 0.05). In responders, CCR5 expression returned to normal levels (P = 1.000 > 0.05). b Compared to control, CXCR3 mRNA levels in active ITP patients were elevated (P = 0.000 < 0.05). CXCR3 expression in responders decreased (P = 0.000 < 0.05), but was still higher than that in control (P = 0.000 < 0.05). c Compared to control, CCR3 mRNA levels in active ITP decreased (P = 0.000 < 0.05); after treatment with HD-DXM, CXCR3 expression in responders increased (P = 0.000 < 0.05). * P < 0.01 vs control and responders, ## P < 0.01 vs control

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