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Table 1 Liver levels of ornithine and citrulline in animals subjected to PH and treated with α-tocopherol and/or putrescine

From: Putrescine treatment reverses α-tocopherol-induced desynchronization of polyamine and retinoid metabolism during rat liver regeneration

Treatment Ornithine Citrulline Ornithine/citrulline ratio
Sham (control) 378 ± 57 529 ± 63 0.71 ± 0.09
PH + vehicle
 6 h post-PH 257 ± 26 438 ± 53 0.59 ± 0.06
 12 h post-PH 345 ± 41 575 ± 81 0.60 ± 0.07
 24 h post-PH 551 ± 77 631 ± 101 0.87 ± 0.12
 48 h post-PH 515 ± 67 746 ± 104 0.69 ± 0.10
 72 h post-PH 458 ± 51 309 ± 37* 1.48 ± 0.23*
PH + VE
 6 h post-PH 513 ± 62** 616 ± 80 0.83 ± 0.10
 12 h post-PH 761 ± 107*,** 614 ± 92 1.24 ± 0.18*,**
 24 h post-PH 569 ± 91 584 ± 99 0.97 ± 0.16
 48 h post-PH 608 ± 85** 507 ± 76 1.20 ± 0.17*,**
 72 h post-PH 746 ± 90*,** 415 ± 54 1.80 ± 0.23*,**
PH + Putrescine
 6 h post-PH 468 ± 80** 440 ± 52 1.06 ± 0.15**
 12 h post-PH 510 ± 77 185 ± 24*,** 2.76 ± 0.39*,**
 24 h post-PH 548 ± 71 601 ± 90 0.91 ± 0.13
 48 h post-PH 705 ± 78* 805 ± 137 0.88 ± 0.12
 72 h post-PH 488 ± 44 303 ± 39* 1.48 ± 0.16*
PH + VE + Putres
 6 h post-PH 983 ± 118*,** 898 ± 135** 1.04 ± 0.14**
 12 h post-PH 587 ± 82** 257 ± 41*,** 2.28 ± 0.34*,**
 24 h post-PH 674 ± 106* 690 ± 97 0.98 ± 0.15
 48 h post-PH 755 ± 78*,** 938 ± 131* 0.80 ± 0.10
 72 h post-PH 535 ± 55 217 ± 27* 2.47 ± 0.28*,**
  1. Results are the mean ± SE of 5 individual observations by experimental point and expressed by gram of liver
  2. PH partial hepatectomy, VE α-tocopherol, and Putres putrescine. Statistical significance, as indicated in *