Fig. 2
ERC treatment markedly attenuated histopathological damage after CCl4 induction. Mice were treated with CCl4 (1 ml/kg body weight and 1:3 diluted in corn oil) to induce acute liver injury, then intravenously administered with ERCs (1 × 106/0.2 ml/mouse, suspended in PBS) 30 min after CCl4 injection, only once in 24 h. Photographs of livers were taken 24 h after CCl4 injection. a indicates gross pathological changes of livers. b Representative photomicrographs of histological sections of liver (200×, haemotoxylin and eosin staining). Livers in the untreated group exhibited more ballooned hepatocytes, apoptosis and necrosis than those in the normal control groups, which were significantly alleviated by ERC treatment (n = 6)