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Table 1 Demographic data

From: Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery

  Controls He-pre He-post He-PP APC p value
N 28 23 22 24 24  
Age ± years 66.7 ± 7.0 62.8 ± 11.7 66.2 ± 7.8 66.2 ± 8.3 66.9 ± 7.6 0.47
Male (%) 22 (82) 21 (91) 20 (83) 20 (83) 21 (88) 0.88
Body Mass Index 28.4 ± 3.7 27.3 ± 2.7 26.7 ± 3.8 27.4 ± 3.7 27.7 ± 3.2 0.55
Risk factors
 Hypertension 16 (59) 9 (39) 13 (57) 10 (42) 13 (54) 0.52
 Hypercholesterolemia 6 (22) 11 (48) 10 (44) 5 (21) 14 (58) 0.023 a
 Smoking 13 (48) 10 (44) 8 (34) 11 (46) 10 (42) 0.89
 Family 12 (44) 9 (39) 7 (30) 9 (38) 13 (54) 0.56
 Myocardial infarction 7 (26) 10 (44) 8 (36) 10 (42) 8 (33) 0.71
 Cerebrovascular accident 0 (0) 0 (0) 0 (0) 1 (4) 0 (0) 0.40
Heart failure
 NYHA I 20 (74) 17 (74) 19 (86) 17 (71) 16 (70) 0.97
 NYHA II 2 (7) 2 (9) 1 (5) 2 (8) 3 (13) 0.97
 NYHA III 5 (19) 4 (17) 2 (9) 4 (17) 4 (17) 0.97
Ejection fraction
 >50 % 21 (81) 16 (73) 12 (57) 16 (67) 19 (90) 0.15
 30–50 % 5 (19) 6 (27) 7 (33) 4 (17) 1 (5) 0.15
Medication
 Salicylate 24 (86) 19 (83) 22 (92) 23 (96) 23 (92) 0.57
 Clopidogrel 9 (32) 9 (39) 12 (50) 9 (38) 4 (16) 0.15
 Statinb 27 (96) 23 (100) 24 (100) 20 (83) 21 (84) 0.04 b
 Beta-blockerc 19 (68) 22 (96) 24 (100) 21 (88) 21 (84) 0.008 c
 ACE inhibitor 10 (36) 8 (35) 10 (42) 4 (17) 11 (44) 0.30
 AT2 receptor blocker 6 (21) 1 (4) 5 (21) 5 (21) 3 (12) 0.40
 Calcium channel blocker 10 (36) 7 (30) 4 (17) 10 (42) 6 (24) 0.35
 Diuretics 6 (21) 4 (17) 4 (17) 7 (29) 4 (16) 0.77
 Nitrates 10 (36) 9 (39) 7 (29) 12 (50) 13 (52) 0.43
 Euroscore 3 (±2) 2 (±3) 3 (±3) 4 (±3) 1 (±3) 0.36
  1. Age and body mass index are presented as mean ± SD; Euroscore is presented as mean (±IQR); other data are numbers and percentage, n (%)
  2. aIn the control group significantly less patients with hypercholesterolemia were present
  3. bUse of statins was significantly lower in our control group compared to other groups
  4. cUse of beta-blockers was significantly lower in our control group compared to other groups
  5. He-Pre helium preconditioning; He-Post helium postconditioning; He-PP helium pre- and postconditioning; APC anesthetic preconditioning
  6. Age and Body Mass Index are presented as mean ± SD; Euroscore is presented as mean (±IQR); other data are numbers and percentage, n (%). In the control group significantly less patients with hypercholesterolemia were present. b Use of statins was significantly lower in our control group compared to other groups. c Use of beta-blockers was significantly lower in our control group compared to other groups
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