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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2

Fig. 2

IA-2 silencing by RNAi leads to reduced SCLC cell proliferation and ACh secretion. a, b Effects of IA-2 RNAi on cell growth in both NCI-H82 and NCI-H345 cells. Cells were treated with IA-2 siRNA for 1–4 days (n = 4). Secreted ACh levels (e, f) and intracellular ACh levels (content) (c, d), were measured after four days of IA-2 siRNA (n = 3). Data (mean ± SE) were derived from three independent experiments performed in triplicate and normalized to total cell numbers. *P < 0.05, **P < 0.01

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