Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study

Table 2 Correlations of functional measures with muscle characteristics in PAD patients (n = 26)

	Pearson correlation coefficients (Prob > \|r\| under H0: Rho = 0, number of observations)
	6-min walk distance (m)		4-min walking velocity, normal-paced (m/s)		4-min walking velocity, fastest-paced (m/s)
	r value	P value	r value	P value	r value	P value
% Type I	0.0067	0.975	0.1422	0.488	0.0785	0.703
% Type IIa	−0.0539	0.798	−0.2054	0.314	−0.2433	0.231
% Type IIa/IIx	0.0456	0.829	0.0210	0.919	0.1435	0.485
Min. feret, Type I	0.3175	0.122	0.4940	0.010	0.4944	0.010
Min. feret, Type II	0.2676	0.196	0.4317	0.028	0.3713	0.062
Min. feret, average	0.3121	0.129	0.4804	0.013	0.4137	0.036
Lectin/fiber^a	0.0537	0.813	−0.0208	0.925	−0.0783	0.723
% Fibers with cavities in SDH^a	−0.1991	0.460	0.4426	0.086	0.0993	0.714
PGC1α mRNA^a	−0.1025	0.686	0.0832	0.743	0.1580	0.531
CREB mRNA^a	0.0750	0.768	−0.2533	0.310	−0.2675	0.283
CTRC1 mRNA^a	0.0431	0.871	−0.2346	0.349	−0.2495	0.318
HIF1α mRNA^a	0.2072	0.409	−0.2480	0.321	−0.1937	0.441

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