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Table 1 Baseline characteristics of study population

From: Triglyceride glucose-waist circumference, a novel and effective predictor of diabetes in first-degree relatives of type 2 diabetes patients: cross-sectional and prospective cohort study

Characteristics

NGT

Prediabetes

Diabetes

Number

657

423

464

Sex (M/F)

256/401

174/249

205/259

Age (years)

47.0 (36.0, 54.0)

52.0 (44.0, 58.0)a

59.0 (50.0, 65.0)a, b

SBP (mmHg)

121.0 (119.0, 122.0)

126.0 (124.0, 127.0)a

129.0 (127.0, 131.0)a, b

DBP (mmHg)

76.0 (75.0, 77.0)

79.0 (78.0, 80.0)a

79.0 (78.0, 80.0)a

BMI (kg/m2)

24.39 (24.03, 24.75)

25.12 (24.68, 25.55)a

25.26 (24.81, 25.70)a

WC (cm)

83.0 (82.1, 83.9)

88.4 (87.3, 89.5)a

92.2 (91.1, 93.3)a, b

VAI

1.70 (1.53, 1.87)

2.39 (2.19, 2.59)a

2.82 (2.62, 3.03)a, b

TyG

8.43 (8.38, 8.48)

8.81 (8.75, 8.87)a

9.21 (9.15, 9.27)a, b

TyG-BMI

206.47 (202.86, 210.08)

222.05 (217.69, 226.42)a

233.45 (228.99, 237.91)a, b

TyG-WC

702.07 (692.13, 712.00)

780.36 (768.35, 792.37)a

851.94 (839.66, 864.22)a, b

TG (mmol/L)

1.33 (1.23, 1.43)

1.71 (1.59, 1.82)a

1.94 (1.82, 2.07)a, b

TC (mmol/L)

4.92 (4.83, 5.00)

5.01 (4.91, 5.11)

5.09 (4.98, 5.19)a

HDL-C (mmol/L)

1.47 (1.44, 1.50)

1.31 (1.27, 1.35)a

1.31 (1.27, 1.34)a

LDL-C (mmol/L)

2.93 (2.87, 2.99)

3.03 (2.96, 3.10)a

3.06 (2.98, 3.13)a

FPG (mmol/L)

5.10 (4.97, 5.22)

5.74 (5.59, 5.89)a

8.65 (8.50, 8.81)a, b

2hPG (mmol/L)

6.06 (5.83, 6.29)

8.65 (8.38, 8.93)a

17.11 (16.83, 17.39)a, b

FINS (μU/ml)

9.23 (8.55, 9.92)

11.19 (10.36, 12.03)a

12.58 (11.73, 13.43)a, b

2hINS (μU/ml)

38.70 (36.09, 41.31)

65.52 (62.36, 68.68)a

43.02 (39.80, 46.25)b

HbA1c (%)

5.50 (5.42, 5.58)

5.75 (5.65, 5.84)a

7.36 (7.27, 7.46)a, b

  1. Data were expressed as median (Interquartile range 25–75 %)
  2. Comparisons among NGT, Prediabetes and Diabetes groups were performed after adjusting for age
  3. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, WC waist circumference, VAI visceral adiposity index, TyG triglyceride glucose index, TyG-BMI combined TyG and BMI, TyG-WC combined TyG and WC, TG triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, FPG fasting plasma glucose, 2hPG 2 h postload plasma glucose, FINS fasting serum insulin, 2hINS 2 h postload serum insulin, HbA1c glycated hemoglobin A1c
  4. aP < 0.05 versus NGT group
  5. bP < 0.05 versus Prediabetes group