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Table 1 Semi-quantitative evaluation of complement staining 30 min post-reperfusion

From: Inhibition of complement improves graft outcome in a pig model of kidney autotransplantation

  

CTL

VEH

rhC1INH

C1q

Glomeruli

++

++

++

Vessels

+

+

+

C3c

Mesengium

++

+++

+++

Glomerular capillary wall

+++

+++

+++

Apex proximal tubules

+++

+++

C4d

Glomeruli

+++

+++++

+++

Peritubular capillaries

++

++++

++

MASP

Tubular basal membrane

++

++

++

MBL

Intratubular

+

+

±

C5b-9

 

No staining

No staining

No staining

Factor B

 

No staining

No staining

No staining

  1. Needle biopsies were performed 30 min after unclamping (45 min post injection) and processed for cryopreservation. Slides were evaluated by fluorescence microscopy by a trained nephropathologist