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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Celecoxib suppresses autophagy and enhances cytotoxicity of imatinib in imatinib-resistant chronic myeloid leukemia cells

Fig. 7

Celecoxib enhances cytotoxicity of imatinib on KBM5 and KBM5-T315I cells. a The two cell lines treated with 0, 20, 40 μM celecoxib and 0, 0.1, 0.2, 0.4, 0.8 μM Imatinib for 24 and 48 h were subjected to MTT assay. Data were mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001. b The two cell lines were exposed to 40 μM celecoxib and 0.4 μM Imatinib for 24 h and Western blot was conducted for the expression of LC3 and cleaved caspase 3. Three independent experiments were conducted, and representative data were shown

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