Micro-RNA-21 (biomarker) and global longitudinal strain (functional marker) in detection of myocardial fibrotic burden in severe aortic valve stenosis: a pilot study

Table 2 Echocardiographic and invasive data

	Mean	SD
Valvular parameters
AVAi (cm²/m²)	0.45	0.09
Max gradient (mmHg)	80.2	16.76
Mean gradient (mmHg)	49.7	7.67
Peak-peak gradient (mmHg)	58.3	15.40
Velocity-ratio	0.18	0.04
Peak velocity (m/sec)	4.4	0.34
Non invasive haemodynamic data
SVi (mL/m²)	38.5	16.08
CI (L/min/m²)	2.5	0.72
CO (L/min)	4.8	1.45
Z_VA (mmHg/ml/m²)	5.9	1.26
Diastolic function parameters
EDPi (mmHg) (invasive)	16.81	6.81
LAVi (mL/m²)	48.2	12.65
E/A	0.8	0.33
E/e’ Average	18.4	8.39
DT (msec)	247.2	93.25
Conventional systolic function parameters (with TDI)
EF %	65.8	10.94
FS %	36.4	7.89
MAPSE (mm)	9.5	1.84
s’ l (cm/s)	6.4	1.50
s’s (cm/s)	5.6	1.49
Left and right ventricular echo parameters
EDDi (cm/m²)	2.52	0.25
EDVi (mL/m²)	50.28	12.95
ESDi (cm)	1.71	0.30
ESVi (mL/m²)	17.47	8.55
LVMi (g/m²)	149.5	20.7
RWT	0.51	0.07
sPAP (mmHg)	30.8	6.46
TAPSE (cm)	1.8	0.25

AVAi indexed aortic valve area, CI cardiac index, CO cardiac output, DT deceleration time, E/A ratio of early to late diastolic mitral filling velocity, E/e′ ratio of early diastolic velocity (PW) to tissue proto-diastolic velocity (TDI), EDDi indexed left ventricular end-diastolic diameter, EDPi invasive left ventricular end-diastolic pressure, EDVi, indexed left ventricular end-diastolic volume, EF, ejection fraction, ESDi, indexed left ventricular end-systolic diameter, ESVi, indexed left ventricular end-systolic volume, FS, fractional shortening, LAVi, indexed left atrial volume, LVMi, indexed left ventricular mass, MAPSE, mitral annular plane systolic excursion, RWT, relative wall thickness, s’L, systolic velocity (TDI) lateral, s’S, systolic velocity (TDI) septal, sPAP, systolic pulmonary arterial pressure, SVi, indexed stroke volume, TAPSE, tricuspid annular plane systolic excursion, Z _VA, valvulo-arterial impedance

ISSN: 1479-5876