Fig. 5

Differential levels of expression of plasmatic miRNA-21 in patients with significant MF (MF % > 10 %). The plasmatic levels of miRNA-21 in patients with high MF (Over Ten = 1) resulted higher respective to the low fibrosis group (Median 5.5043 vs. 0.8854; p = 0.03). The table shows principal differences in clinical profiles. AVAi indexed aortic valve area, BNP brain natriuretic peptide, DT deceleration time, E/A ratio of early to late diastolic mitral filling velocity (PW), EF ejection fraction, eGFR estimated glomerular filtration rate, GLS global longitudinal strain, LVMi indexed left ventricular mass, MF Myocardial Fibrosis, RWT relative wall thickness