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Table 1 Characteristics, redox status, CD26-expression and muscle fatigue parameters of ME/CFS patients and control subjects

From: Association of biomarkers with health-related quality of life and history of stressors in myalgic encephalomyelitis/chronic fatigue syndrome patients

  ME/CFS (n = 32) Controls (n = 11)
Age (years) 42 ± 7 46 ± 5
Sex ratio (F/M) 24/12 6/5
ME/CFS duration (y) 5 ± 1  
At rest
 RAA/TBARS 91 ± 19* 129 ± 15
 CD26-expression (AU) 2.72 + 0.09* 3.60 ± 0.09
End exercise   
 VO2max (ml min−1 kg−1) 23 ± 1 26 ± 4
 Δ M-wave (%) −41 ± 8** +8 ± 6
 ΔTBARS (%) +50 ± 10** +15 ± 7
  1. At rest: RAA/TBARS: ratio of antioxidant response (Reduced ascorbic acid, RAA) to lipid peroxidation (Thiobarbituric acid reactive substances, TBARS); CD26-expression measured via DPP-IV activity (AU: arbitrary unit)
  2. Exercise: VO2 max (maximal oxygen uptake); ΔM-wave amplitude: (maximal decrease in M-wave amplitude evoked in the rectus femoris); ΔTBARS (maximal increase in TBARS post-exercise) (Mean + SEM; * p < 0.05; ** p < 0.01)