Table 1 Dose finding study
From: Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury
Administration | Injections | Harvest | |||||
|---|---|---|---|---|---|---|---|
Fetal | −48 h saline | −48 h OM low | −48 h OM high | −24 h saline | −24 h OM low | −24 h OM high | At delivery |
Maternal | −48 h saline | −48 h OM low | −24 h saline | −24 h OMlow | −8 h saline | −8 h OM low | At delivery |
Neonatal | Daily saline (normoxia) | Daily OM high (normoxia) | Daily saline (hyperoxia) | Daily OM low (hyperoxia) | Daily OM med (hyperoxia) | Daily OM high (hypreoxia) | Day 3 –day 5 |