Skip to main content

Table 3 Muscle structure in both diaphragm and gastrocnemius muscles of all groups of mice of the 35-week cohort

From: Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema

 

Controls

U

E–U

Diaphragms

 Fiber type proportions

  Type I fibres (%)

8.1 (1.00)

8.2 (0.80)

7.7 (1.05)

  Type II fibres (%)

91.9 (1.00)

91.8 (0.80)

92.3 (1.05)

 Cross-sectional area

  Type I fibres (μm2)

257.9 (33.1)

221.7 (30.3)*

182.4 (12.8)***, §

  Type II fibres (μm2)

377.9 (30.1)

326.7 (47.6)*

258.8 (28.1)***, §§

Gastrocnemius

 Fiber type proportions

  Type I fibres (%)

22.7 (6.26)

24.0 (4.73)

20.5 (3.25)

  Type II fibres (%)

77.3 (6.26)

76.0 (4.73)

77.5 (3.25)

 Cross-sectional area

   

  Type I fibres (μm2)

824.7 (155.2)

680.5 (67.6)*

609.8 (74.6)***

  Type II fibres (μm2)

835.3 (100.7)

721.9 (70.4)*

665.2 (80.0)***

  1. Variables are presented mean (standard deviation)
  2. U urethane, E–U elastase–urethane
  3. Statistical significance: * p ≤ 0.05 and *** p ≤ 0.001 between any of the experimental groups and the control mice
  4. §p ≤ 0.05 and §§p ≤ 0.01 between urethane and elastase-urethane groups of mice
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us