Fig. 12

a Mean values and standard deviation of myogenin, in diaphragm (white bars) and gastrocnemius (black bars) muscles as measured by optical densities. Statistical significance is represented as follows: n.s.: non-significant and ***p ≤ 0.001 between any of the intervention groups (U and E–U) and control mice. b Mean values and standard deviation of PPAR-α, in diaphragm (white bars) and gastrocnemius (black bars) muscles as measured by optical densities. Statistical significance is represented as follows: n.s.: non-significant, *p ≤ 0.05 and ***p ≤ 0.001 between any of the intervention groups (U and E–U) and control mice. c Mean values and standard deviation of PPAR-gamma, in diaphragm (white bars) and gastrocnemius (black bars) muscles as measured by optical densities. Statistical significance is represented as follows: *p ≤ 0.05 and ***p ≤ 0.001 between any of the intervention groups (U and E–U) and control mice. d Mean values and standard deviation of PGC-1α, in diaphragm (white bars) and gastrocnemius (black bars) muscles as measured by optical densities. Statistical significance is represented as follows: n.s.: non-significant between any of the intervention groups (U and E–U) and control mice. a.u. arbitrary units, E–U elastase–urethane, OD optical densities, PPAR- peroxisome proliferator-activated receptor alpha; PPAR- peroxisome proliferator-activated receptor gamma, PGC-1 peroxisome proliferator-activated receptor gamma coactivator-1α, U urethane