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Table 1 Clinical and laboratory characteristics of coronary patients according to the presence of type 2 diabetes mellitus, and non-CAD patients

From: Type 2 diabetes is associated with decreased PGC1α expression in epicardial adipose tissue of patients with coronary artery disease

 

NCAD

CAD-NDM2

P value*

CAD-DM2

P value**

P value***

P value

Gender, n (M/F)

12/11

20/2

0.007

18/4

0.057

0.664

0.01

Age (years)

62 ± 11

63 ± 11

0.762

65 ± 9

0.323

0.513

0.619

BMI (kg/m2)

27.8 ± 5.3

28.2 ± 6.4

0.820

29.8 ± 5.7

0.229

0.386

0.481

LVEF (%)

57.7 ± 12.4

51.7 ± 8.0

0.05

51.2 ± 4.2

0.024

0.796

0.031

Risk factors, n (%)

 Dyslipidemia

10 (43.5)

15 (68.2)

0.136

18 (81.8)

0.013

0.487

0.021

 Hypertension

21 (91.3)

17 (77.2)

0.242

20 (90.9)

0.99

0.412

0.296

 Current smoking

7 (30.4)

14 (63.6)

0.04

7 (31.8)

0.99

0.07

0.04

 CVA

2 (8.7)

1 (4.5)

0.578

2 (9.1)

0.962

0.549

0.812

Medications, n (%)

 Aspirin

13 (56.5)

8 (36.4)

0.236

14 (63.6)

0.763

0.131

0.170

 Statin

9 (39.1)

8 (36.4)

0.85

12 (54.5)

0.376

0.364

0.421

 ACEI/ARB

6 (26.1)

5 (22.7)

0.796

10 (45.4)

0.221

0.202

0.213

 Beta-blocker

15 (65.2)

8 (36.4)

0.076

14 (63.6)

0.912

0.131

0.094

Biochemical data

 Glucose (mg/dL)

106.00 ± 18.93

103.00 ± 20.10

0.61

153.86 ± 41.51

<0.0001

<0.0001

<0.0001

 Cholesterol (mg/dL)

161.88 ± 41.98

165.47 ± 30.17

0.74

143.88 ± 34.29

0.12

0.032

0.109

 LDL-cholesterol (mg/dL)

97.24 ± 31.76

102.95 ± 27.1

0.52

81.68 ± 23.29

0.068

0.008

0.04

 HDL-cholesterol (mg/dL)

40.70 ± 14.32

36.47 ± 11.43

0.28

29.75 ± 6.44

0.002

0.020

0.008

 Triglycerides (mg/dL)

119.76 ± 44.59

153.23 ± 61.3

0.041

187.58 ± 55.12

<0.0001

0.057

0.0005

 HbA1c

5.46 ± 0.63

5.91 ± 0.61

0.02

7.51 ± 0.90

<0.0001

<0.0001

<0.0001

 Creatinine (mg/dL)

1.00 ± 0.32

1.24 ± 0.80

0.16

1.20 ± 0.51

0.11

0.79

0.329

  1. Comparison between the results of the different groups was made with the Student’s t test or with the analysis of variance (ANOVA) and Chi square test for continuous and categorical data, respectively. Values were considered to be statistically significant when P < 0.05
  2. CAD coronary artery disease; n no. of subjects; BMI body mass index; LVEF left ventricle ejection fraction; CVA cerebrovascular accident; ACEI angiotensin converting enzyme inhibitor; ARB angiotensin II receptor blocker; LDL low-density lipoprotein; HDL high-density lipoprotein; HbA1c glycated hemoglobin
  3. p value: overall comparison for all groups
  4. p value*: NCAD vs CAD-NDM2 comparison
  5. p value**: NCAD- vs CAD-DM2 comparison
  6. p value***: CAD-NDM2 vs CAD-DM2 comparison