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Table 4 WORMS score before administration of treatments and 6 and 12 months afterwards

From: Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)

Time Control BM-MSCs
Low-dose High-dose
Baseline 79 (41, 94) 75 (64, 107) 60 (53, 84)
6 months 78 (34, 107) 70 (57, 126) 53 (51, 90)
12 months 83 (25, 95) 90 (67, 140) 53 (46, 82)
12 months evolution −0.5 (−16, 15) 2.5 (−3, 25) −4 (−22, 2)
  1. The overall WORMS scores at baseline and 6 and 12 months afterwards are presented as the median (IQR) of each group. The evolution within each treatment group at 12 months is also presented, and was calculated by subtracting for each patient the values at 12 months from the corresponding baseline values. Data are the median (IQR) of each group