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Table 3 Associations of MBL levels with cardiovascular events and cardiac events in 107 chronic hemodialysis patients

From: Strong predictive value of mannose-binding lectin levels for cardiovascular risk of hemodialysis patients

  Cardiovascular events
Low MBL Log MBL continuous
HR 95 % CI P HR (per SD) 95 % CI P
Model 1 2.64 1.36–5.13 0.004 0.64 0.46–0.90 0.01
Model 2 2.75 1.39–5.44 0.004 0.61 0.43–0.88 0.008
Model 3 2.94 1.45–5.94 0.003 0.61 0.42–0.89 0.01
Model 4 3.55 1.70–7.40 0.001 0.58 0.40–0.84 0.004
Model 5 3.98 1.88–8.42 <0.001 0.56 0.38–0.81 0.002
  1. Model 1: crude
  2. Model 2: adjusted for age and gender
  3. Model 3: adjusted for model 2 plus ultrafiltration volume and dialysis vintage
  4. Model 4: adjusted for model 3 plus cardiovascular history, diabetes and post-HD systolic blood pressure
  5. Model 5: adjusted for model 4 plus hsCRP
  6. Data are presented as hazard ratio (HR) plus 95 % confidence interval (CI) according to the cut-off of MBL and per standard deviation (SD) MBL decrease
  7. Italic values used to show which statistical testing was significant (below 0.05)
  8. MBL mannose-binding lectin; HD hemodialysis; hsCRP high sensitive C-reactive protein
  Cardiac events
Model 1 2.60 1.10–6.18 0.03 0.71 0.46–1.10 0.1
Model 2 2.49 1.04–5.96 0.04 0.73 0.46–1.16 0.2
Model 3 2.65 1.08–6.55 0.03 0.74 0.47–1.18 0.2
Model 4 3.82 1.48–9.87 0.006 0.62 0.38–1.01 0.06
Model 5 3.96 1.49–10.54 0.006 0.59 0.35–0.98 0.04
  1. Model 1: crude
  2. Model 2: adjusted for age and gender
  3. Model 3: adjusted for model 2 plus ultrafiltration volume and dialysis vintage
  4. Model 4: adjusted for model 3 plus cardiovascular history, diabetes and post-HD systolic blood pressure
  5. Model 5: adjusted for model 4 plus hsCRP
  6. Data are presented as hazard ratio (HR) plus 95 % confidence interval (CI) according to the cut-off of MBL and per standard deviation (SD) MBL decrease
  7. Italic values used to show which statistical testing was significant (below 0.05)
  8. MBL mannose-binding lectin; HD hemodialysis; hsCRP high sensitive C-reactive protein