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Table 3 Associations of MBL levels with cardiovascular events and cardiac events in 107 chronic hemodialysis patients

From: Strong predictive value of mannose-binding lectin levels for cardiovascular risk of hemodialysis patients

 

Cardiovascular events

Low MBL

Log MBL continuous

HR

95 % CI

P

HR (per SD)

95 % CI

P

Model 1

2.64

1.36–5.13

0.004

0.64

0.46–0.90

0.01

Model 2

2.75

1.39–5.44

0.004

0.61

0.43–0.88

0.008

Model 3

2.94

1.45–5.94

0.003

0.61

0.42–0.89

0.01

Model 4

3.55

1.70–7.40

0.001

0.58

0.40–0.84

0.004

Model 5

3.98

1.88–8.42

<0.001

0.56

0.38–0.81

0.002

 

Cardiac events

Model 1

2.60

1.10–6.18

0.03

0.71

0.46–1.10

0.1

Model 2

2.49

1.04–5.96

0.04

0.73

0.46–1.16

0.2

Model 3

2.65

1.08–6.55

0.03

0.74

0.47–1.18

0.2

Model 4

3.82

1.48–9.87

0.006

0.62

0.38–1.01

0.06

Model 5

3.96

1.49–10.54

0.006

0.59

0.35–0.98

0.04

  1. Model 1: crude
  2. Model 2: adjusted for age and gender
  3. Model 3: adjusted for model 2 plus ultrafiltration volume and dialysis vintage
  4. Model 4: adjusted for model 3 plus cardiovascular history, diabetes and post-HD systolic blood pressure
  5. Model 5: adjusted for model 4 plus hsCRP
  6. Data are presented as hazard ratio (HR) plus 95 % confidence interval (CI) according to the cut-off of MBL and per standard deviation (SD) MBL decrease
  7. Italic values used to show which statistical testing was significant (below 0.05)
  8. MBL mannose-binding lectin; HD hemodialysis; hsCRP high sensitive C-reactive protein