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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Percutaneous irreversible electroporation for breast tissue and breast cancer: safety, feasibility, skin effects and radiologic–pathologic correlation in an animal study

Fig. 5

After IRE, apoptosis in the breast was detected. a (×200) Caspase-3 immunohistochemistry and cytosolic staining in ducts and alveoli. b (×200) Cytosolic staining was negative in the control group. c (×400) One day after IRE, the TUNEL assays indicated that most nuclei stained positive, indicating cell apoptosis. d (×400) No apoptosis was observed in the control group (black arrow). e (×400) One week after IRE, the breast tissue was normal. f One week after IRE, the architecture and glandular epithelial cells of the sebaceous glands and sweat glands were normal. g The hair roots in the breast skin were normal. h (×200) One week after IRE, the squamous epithelial cells in the breast skin were normal

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